The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2018
Filed:
Mar. 01, 2016
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Shih-Chia Hsiao, Oakland, CA (US);
Matthew B. Francis, Berkeley, CA (US);
Carolyn Bertozzi, Berkeley, CA (US);
Richard Mathies, Walnut Creek, CA (US);
Ravi Chandra, Newton, MA (US);
Erik Douglas, Oakland, CA (US);
Amy Twite, Berkeley, CA (US);
Nicholas Toriello, San Carlos, CA (US);
Hiroaki Onoe, Tokyo, JP;
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/07 (2010.01); C07H 21/00 (2006.01); C12N 5/0789 (2010.01); C12N 5/04 (2006.01); C12N 5/00 (2006.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
C12N 5/0006 (2013.01); A61K 47/6901 (2017.08);
Abstract
The present invention provides conjugates of DNA and cells by linking the DNA to a native functional group on the cell surface. The cells can be without cell walls or can have cell walls. The modified cells can be linked to a substrate surface and used in assay or bioreactors.