The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2018

Filed:

Nov. 22, 2013
Applicant:

Suzhou Alphamab Co., Ltd., Suzhou, Jiangsu, CN;

Inventors:

Ting Xu, Jiangsu, CN;

Kangping Guo, Jiangsu, CN;

Lihong Yun, Jiangsu, CN;

Assignee:

Suzhou Alphamab Co, Ltd., Suzhou Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/59 (2006.01); A61K 38/24 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/59 (2013.01); A61K 38/24 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract

Disclosed herein is a gonadotropin fusion protein or a thyroid stimulating hormone fusion protein, a method for preparing the same and use thereof. β-subunit of the gonadotropin or thyroid stimulating hormone is fused to an Fc fragment directly or indirectly through a linker, and α-subunit binds to the β-subunit via an affinity between the α-subunit and the β-subunit. The fusion protein has a prolonged half-life and less fluctuating activity.


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