The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2018

Filed:

Apr. 22, 2014
Applicants:

GE Healthcare Limited, Buckinghamshire, GB;

GE Healthcare As, Oslo, NO;

Inventors:

Torild Wickstrom, Oslo, NO;

Dirk-Jan In't Veld, Oslo, NO;

Nigel John Osborn, Amersham, GB;

Julian Grigg, Amersham, GB;

Anthony Wilson, Waddesdon, GB;

Assignees:

GE HEALTHCARE AS, Oslo, NO;

GE HEALTHCARE LIMITED, Buckinghamshire, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 13/04 (2006.01); C07H 1/00 (2006.01);
U.S. Cl.
CPC ...
C07H 13/04 (2013.01); C07H 1/00 (2013.01);
Abstract

The present invention relates to a method for improving stability of non fluoridated sugar derivatives, and in particular glucose derivatives such as 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-β-D-mannopyranose which are used as precursors for production of radiofluoridated sugar derivatives for use in in vivo imaging procedures such as positron emission tomography (PET). The method comprises storing the non fluoridated sugar derivative in an organic solvent. The resultant formulations of the non fluoridated sugar derivative and cassettes for automated synthesis apparatus comprising the same are also claimed.


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