The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2018

Filed:

Jun. 11, 2015
Applicants:

Ucb Biopharma Sprl, Brussels, BE;

Katholieke Universiteit Leuven, K.u. Leuven R&d, Leuven, BE;

Inventors:

Daniel James Ford, Slough, GB;

Qiuya Huang, Leuven, BE;

Judi Charlotte Neuss, Slough, GB;

James Thomas Reuberson, Slough, GB;

Bart Vanderhoydonck, Diest, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A01N 43/90 (2006.01); C07D 498/04 (2006.01); C07D 487/04 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61K 31/519 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01);
Abstract

A series of fused bicyclic heteroaromatic derivatives of formula (IA) or (IB), as defined herein, being selective inhibitors of phosphatidylinositol-4-kinase IIIβ (PI4KIIIβ) activity, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases and malaria; and organ and cell transplant rejection.


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