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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9969741 B1

PDFFull Text
Date of Patent:
May. 15, 2018

Filed:

Jun. 17, 2015

Pyrazolotriazines as inhibitors of nucleases

Applicant:

Masarykova Univerzita, Brno, CZ;

Inventors:

Jiri Damborsky, Brno, CZ;

Fedor Nikulenkov, St. Petersburg, RU;

Alexandra Sisakova, Slanec, SK;

Stepan Havel, Cernozice, CZ;

Lumir Krejci, Brno, CZ;

Benoit Carbain, Montigny-le-Bretonneux, FR;

Jan Brezovsky, Brno, CZ;

Lukas Daniel, Zlin, CZ;

Kamil Paruch, Tisnov, CZ;

Assignee:

MASARYKOVA UNIVERZITA, Brno, CZ;

Attorney:

Notaro, Michalos & Zaccaria P.C.

Primary Examiner:

Venkataraman Balasubramanian

Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/53 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/53 (2013.01);
Abstract

The invention provides compounds represented by the structural formula (1): wherein R, R, Rand Rare as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

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Damborsky, Jiri. (2018). Pyrazolotriazines as inhibitors of nucleases (U.S. Patent No. 9969741). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9969741

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