The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2018
Filed:
Oct. 14, 2016
Applicant:
Opko Health, Inc., Miami, FL (US);
Inventors:
Anandan Palani, Bridgewater, NJ (US);
Xianhai Huang, Warren, NJ (US);
Dong Xiao, Warren, NJ (US);
Sunil Paliwal, Monroe Township, NJ (US);
Hon-Chung Tsui, East Brunswick, NJ (US);
Michelle Laci Wrobleski, Whitehouse Station, NJ (US);
Ashwin U. Rao, Avenel, NJ (US);
Cheng Wang, Summit, NJ (US);
Sapna S. Shah, Jamesburg, NJ (US);
Neng-Yang Shih, Warren, NJ (US);
Assignee:
OPKO Health, Inc., Miami, FL (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 515/00 (2006.01); C07D 401/04 (2006.01); C07D 211/66 (2006.01); C07D 211/76 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01); C07D 498/20 (2006.01); A61K 31/451 (2006.01); A61K 31/4523 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 45/06 (2006.01); C07D 211/60 (2006.01); A61K 31/4178 (2006.01); A61K 31/573 (2006.01); C07D 211/56 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 31/4178 (2013.01); A61K 31/451 (2013.01); A61K 31/454 (2013.01); A61K 31/4523 (2013.01); A61K 31/4545 (2013.01); A61K 31/573 (2013.01); A61K 45/06 (2013.01); C07D 211/56 (2013.01); C07D 211/60 (2013.01); C07D 211/66 (2013.01); C07D 211/76 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01); C07D 498/20 (2013.01);
Abstract
A compound having the general structure shown in Formula I: or pharmaceutically acceptable salts and/or solvates thereof are useful in treating diseases or conditions mediated by NKreceptors, for example various physiological disorders, symptoms or diseases, including emesis, depression, anxiety and cough.