The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2018
Filed:
Mar. 13, 2014
Takeda Pharmaceutical Company Limited, Chuo-ku, Osaka-shi, JP;
Jiro Fujiyasu, Tokyo, JP;
Toru Asano, Tokyo, JP;
Susumu Yamaki, Tokyo, JP;
Osamu Kaneko, Tokyo, JP;
Yuka Koike, Tokyo, JP;
Tomoyoshi Imaizumi, Tokyo, JP;
Yasuharu Urano, Tokyo, JP;
Tomohki Satou, Tokyo, JP;
Satoshi Sasamura, Tokyo, JP;
Takeda Pharmaceutical Company Limited, Osaka, JP;
Abstract
[Problem] To provide a compound which is useful as an agent for preventing and/or treating kidney diseases. [Means for Solution] The present inventors have studied compounds having a trypsin inhibitory activity, and have confirmed that a guanidinobenzoic acid ester compound has a trypsin inhibitory activity, thereby completing the present invention. The guanidinobenzoic acid ester compound of the present invention can be used as an agent for preventing and/or treating kidney diseases (for example, chronic kidney disease, acute glomerulonephritis, acute kidney injury, and the like) as an agent which will substitute low-protein diet therapy, and/or as an agent for preventing and/or treating trypsin-related diseases (for example, chronic pancreatitis, gastroesophageal reflux disease, hepatic encephalopathy, influenza, and the like).