The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2018
Filed:
Feb. 23, 2017
Applicant:
Lung Biotechnology Pbc, Silver Spring, MD (US);
Inventors:
Vijay Sharma, Olney, MD (US);
Hitesh Batra, Herndon, VA (US);
Sudersan Tuladhar, Silver Spring, MD (US);
Assignee:
Lung Biotechnology PBC, Silver Spring, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/93 (2006.01); C07C 259/06 (2006.01); C07F 7/18 (2006.01); C07F 9/28 (2006.01); C07F 9/40 (2006.01);
U.S. Cl.
CPC ...
C07D 307/93 (2013.01); C07C 259/06 (2013.01); C07F 7/1844 (2013.01); C07F 7/1892 (2013.01); C07F 9/28 (2013.01); C07F 9/4006 (2013.01);
Abstract
An improved method is described for making single isomers of synthetic benzoprostacyclin analog compounds, in particular the pharmacologically active 314-d isomer of beraprost. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds.