The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2018

Filed:

Dec. 19, 2014
Applicants:

Crystal Pharmatech, Inc., North Brunswick, NJ (US);

Crystal Pharmatech Co., Ltd., Jiangsu, CN;

Suzhou Pengxu Pharmatech Co., Ltd., Suzhou Jiangsu, CN;

Inventors:

Minhua Chen, Scotch Plains, NJ (US);

Yanfeng Zhang, Suzhou, CN;

Chaohui Yang, Suzhou, CN;

Xiaoyu Zhang, Suzhou, CN;

Peng Wang, Forest Hills, NY (US);

Pixu Li, Suzhou, CN;

Assignees:

Crystal Pharmatech Co., Ltd., Suzhou, Jiangsu, CN;

Suzhou Pengxu Pharmatech Co., Ltd., Suzhou, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/12 (2006.01); C07C 59/06 (2006.01); C07D 207/16 (2006.01);
U.S. Cl.
CPC ...
C07D 249/12 (2013.01); C07C 59/06 (2013.01); C07D 207/16 (2013.01); C07B 2200/13 (2013.01);
Abstract

Novel salts and cocrystals of lesinurad, processes for their preparation, pharmaceutical compositions comprising these new salt forms and co-crystals, and use of them for treating or delaying progression or onset of diseases or disorders related to activity of uric acid transport 1 (URAT1) proteins are disclosed. These novel forms were characterized by X-ray powder diffraction, differential scanning calorimetry, and other techniques. They can be readily prepared and are suitable for preparation of solid dosage forms owing to their ease of handling and superior pharmacological properties.


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