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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9969693 B1

PDFFull Text
Date of Patent:
May. 15, 2018

Filed:

Aug. 17, 2016

6-heteroaryloxy- or 6-aryloxy-quinoline-2-carboxamides and method of use

Applicant:

Abbvie Inc., North Chicago, IL (US);

Inventors:

Andrew Bogdan, Evanston, IL (US);

Marlon D. Cowart, Round Lake Beach, IL (US);

David A. DeGoey, Salem, WI (US);

Tammie K. Jinkerson, Herington, KS (US);

John R. Koenig, Chicago, IL (US);

Michael E. Kort, Lake Bluff, IL (US);

Bo Liu, Waukegan, IL (US);

Mark A. Matulenko, Libertyville, IL (US);

Derek W. Nelson, Highland Park, IL (US);

Meena V. Patel, Green Oaks, IL (US);

Hillary Peltier, Evanston, IL (US);

Marc J. Scanio, Libertyville, IL (US);

Brian D. Wakefield, Vernon Hills, IL (US);

Assignee:

AbbVie Inc., North Chicago, IL (US);

Attorney:
Primary Examiner:

D Margaret M Seaman

Int. Cl.
CPC ...
C07D 215/48 (2006.01); C07D 401/12 (2006.01); C07D 409/14 (2006.01); C07D 487/08 (2006.01); C07D 401/14 (2006.01); C07D 487/04 (2006.01); C07D 405/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 215/48 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 487/08 (2013.01);
Abstract

Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein R, R, and Rare as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Na1.7 and/or Na1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.

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