The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2018

Filed:

Dec. 22, 2014
Applicant:

Norgine B.v., Amsterdam Zuid-Ost, NL;

Inventors:

Rajagopal Bakthavatchalam, Bangalore, IN;

Manas Kumar Basu, Ghaziabad, IN;

Ajit Kumar Behera, Dist-nayagarh, IN;

Chandregowda Venkateshappa, Bangalore, IN;

Christopher Alexander Hewson, Middlesex, GB;

Sanjay Venkatachalapathi Kadnur, Bangalore, IN;

Sarkis Barret Kalindjian, Middlesex, GB;

Bheemashankar Kulkarni, Bangalore, IN;

Rohit Saxena, Lucknow, IN;

Juluri Suresh, Hyderabad, IN;

Vellarkad Viswanathan, Bangalore, IN;

Mohd Zainuddin, Kanpur, IN;

Akila Parvathy Dharshinis, Thruneveli, IN;

Rajenda Kristam, Bangalore, IN;

Assignee:

Norgine B.V., Amsterdam Zuid-Ost, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/50 (2006.01); C07D 413/14 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 409/04 (2006.01); C07D 417/04 (2006.01); C07D 405/04 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 209/50 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 405/04 (2013.01); C07D 409/04 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01);
Abstract

The present invention relates to compounds useful as CCR9 modulators, to compositions containing them, to methods of making them, and to methods of using them. In particular, the present invention relates to compounds capable of modulating the function of the CCR9 receptor by acting as partial agonists, antagonists or inverse agonists. Such compounds may be useful to treat, prevent or ameliorate a disease or condition associated with CCR9 activation, including inflammatory and immune disorder diseases or conditions such as inflammatory bowel diseases (IBD).


Find Patent Forward Citations

Loading…