The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2018
Filed:
Apr. 20, 2015
Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, CN;
Dazhuo Shi, Beijing, CN;
Jiangang Liu, Beijing, CN;
Fuhai Zhao, Beijing, CN;
Xin Wang, Beijing, CN;
Dawu Zhang, Beijing, CN;
Peili Wang, Beijing, CN;
Jianpeng Du, Beijing, CN;
Yuanyuan Cui, Beijing, CN;
Lei Zhang, Beijing, CN;
Kai Cui, Beijing, CN;
Zhengcai Zhang, Beijing, CN;
Abstract
Disclosed is a stent with a drug coating for preventing and treating restenosis, comprising a stent and a drug coating covering the surface of the stent. The active ingredients in the drug coating are guaiane sesquiterpene compounds P1, P2 and P3. P1 is Zedoalactone B, P2 is a stereoisomer of P1, and P3 is Zedoarondiol. Compared with an existing sirolimus eluting stent, the present drug eluting stent can inhibit the intimal hyperplasia and the inflammatory reactions of vascular walls, and promote the endothelialization of blood vessels after the stent is implanted, and thus can prevent the long-term thrombotic complications; and has the advantages of small dosage, low cost, and no toxic side effect.