The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2018
Filed:
Nov. 19, 2014
Applicant:
Cornell University, Ithaca, NY (US);
Inventors:
Jason Spector, New York, NY (US);
Abraham D. Stroock, Ithaca, NY (US);
John Morgan, Minneapolis, MN (US);
Assignee:
CORNELL UNIVERSITY, Ithaca, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61L 27/48 (2006.01); A61L 27/26 (2006.01); A61K 9/16 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); A61L 27/60 (2006.01); A61L 26/00 (2006.01); A61L 27/44 (2006.01);
U.S. Cl.
CPC ...
A61L 27/48 (2013.01); A61K 9/0024 (2013.01); A61K 9/16 (2013.01); A61K 9/1635 (2013.01); A61K 9/1647 (2013.01); A61L 26/008 (2013.01); A61L 26/0052 (2013.01); A61L 27/26 (2013.01); A61L 27/44 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 27/60 (2013.01); A61L 2300/412 (2013.01); A61L 2300/602 (2013.01);
Abstract
Disclosed herein are tissue scaffold materials with microspheres of one density embedded in hydrogel of a different density. The disclosed materials have improved ability to facilitate cellular invasion and vascularization for wound healing and tissue regeneration. The inventors have found that materials having components with different densities promotes invasion of cells, including desirable cells such as fibroblasts and endothelial precursor cells, into the scaffold.