The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2018

Filed:

Nov. 12, 2014
Applicant:

Verily Life Sciences Llc, Mountain View, CA (US);

Inventors:

Alberto Clemente Vitari, San Francisco, CA (US);

Joshua Simon Klein, Mountain View, CA (US);

Jerrod Joseph Schwartz, San Francisco, CA (US);

Andrew Homyk, Belmont, CA (US);

Marija Pavlovic, Mountain View, CA (US);

Assignee:

Verily Life Sciences LLC, Mountain View, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/05 (2006.01); A61K 47/48 (2006.01); A61K 49/00 (2006.01); A61K 47/30 (2006.01); A61M 5/00 (2006.01); A61B 5/00 (2006.01); G01R 33/56 (2006.01); A61B 5/145 (2006.01); A61K 49/18 (2006.01); A61K 51/12 (2006.01); A61B 8/08 (2006.01); A61B 6/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48884 (2013.01); A61B 5/0071 (2013.01); A61B 5/0515 (2013.01); A61B 5/14546 (2013.01); A61B 5/681 (2013.01); A61K 47/30 (2013.01); A61K 47/4823 (2013.01); A61K 47/48238 (2013.01); A61K 47/48569 (2013.01); A61K 49/0002 (2013.01); A61K 49/0004 (2013.01); A61K 49/1824 (2013.01); A61K 51/1244 (2013.01); A61M 5/007 (2013.01); G01R 33/5601 (2013.01); A61B 6/481 (2013.01); A61B 8/481 (2013.01);
Abstract

A system is provided which includes nanoparticle conjugates configured to bind with a tumor cell, the nanoparticle conjugate comprising a nanoparticle, at least one targeting entity bound to the nanoparticle, and at least one shielding entity that shields at the at least one targeting entity, the nanoparticle, or both; a body-mountable device mounted on an external surface of a living body and configured to detect a tumor cell binding response signal transmitted through the external surface, wherein the tumor cell binding response signal is related to binding of the nanoparticle conjugates with one or more tumor cells; and a processor configured to non-invasively detect the one or more tumor cells based on the tumor cell response signal. Nanoparticle conjugates and methods for use for treating or imaging tumor cells are also provided.


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