The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2018
Filed:
Dec. 18, 2008
Applicants:
Brad N. Taylor, Providence, RI (US);
Rajeshwari Mehta, Orland Park, IL (US);
Tohru Yamada, Lombard, IL (US);
Craig Beattie, Chicago, IL (US);
Tapas Das Gupta, River Forest, IL (US);
Inventors:
Brad N. Taylor, Providence, RI (US);
Rajeshwari Mehta, Orland Park, IL (US);
Tohru Yamada, Lombard, IL (US);
Craig Beattie, Chicago, IL (US);
Tapas Das Gupta, River Forest, IL (US);
Assignee:
Other;
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/03 (2006.01); C07K 14/195 (2006.01); C07K 14/21 (2006.01); C07K 14/35 (2006.01); A61K 47/48 (2006.01); A61K 49/00 (2006.01); C07K 14/415 (2006.01); C12N 9/02 (2006.01); G01N 33/50 (2006.01); G01N 33/569 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); A61K 38/03 (2013.01); A61K 49/0002 (2013.01); A61K 49/0032 (2013.01); A61K 49/0056 (2013.01); C07K 14/195 (2013.01); C07K 14/21 (2013.01); C07K 14/35 (2013.01); C07K 14/415 (2013.01); C12N 9/0004 (2013.01); G01N 33/5011 (2013.01); G01N 33/569 (2013.01); A61K 38/00 (2013.01); G01N 2510/00 (2013.01);
Abstract
The present invention discloses methods and materials for killing and/or inhibiting the growth of a cancer cell via preferential entry of a cytotoxic compound. Preferential entry of the cytotoxic compound is accomplished by the use of protein transduction domains derived from cupredoxins, including the p18 and p28 truncations of azurin.