The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2018
Filed:
Jun. 27, 2016
Applicant:
The Board of Trustees of the Leland Stanford Junior University, Standford, CA (US);
Inventors:
Karl Deisseroth, Stanford, CA (US);
Kay Tye, Cambridge, MA (US);
Lief Fenno, San Francisco, CA (US);
Assignee:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2006.01); A61K 38/17 (2006.01); A01K 67/027 (2006.01); A61K 49/00 (2006.01); A61B 5/16 (2006.01); A61N 5/06 (2006.01); A61K 9/00 (2006.01); A61K 48/00 (2006.01); C07K 14/705 (2006.01); C12N 7/00 (2006.01); C12N 15/85 (2006.01); C12N 15/86 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 38/177 (2013.01); A01K 67/0275 (2013.01); A01K 67/0278 (2013.01); A61B 5/165 (2013.01); A61K 9/0019 (2013.01); A61K 41/00 (2013.01); A61K 48/0058 (2013.01); A61K 49/0004 (2013.01); A61K 49/0008 (2013.01); A61N 5/062 (2013.01); C07K 14/705 (2013.01); C12N 7/00 (2013.01); C12N 15/8509 (2013.01); C12N 15/86 (2013.01); G01N 33/5088 (2013.01); A01K 2217/072 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0356 (2013.01); A01K 2267/0393 (2013.01); C12N 2015/859 (2013.01); C12N 2750/14143 (2013.01); C12N 2799/025 (2013.01);
Abstract
Provided herein are animals expressing light-responsive opsin proteins in the basal lateral amygdala of the brain and methods for producing the same wherein illumination of the light-responsive opsin proteins causes anxiety in the animal. Also provided herein are methods for alleviating and inducing anxiety in an animal as well as methods for screening for a compound that alleviates anxiety in an animal.