The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2018

Filed:

Oct. 02, 2017
Applicant:

Celgene Corporation, Summit, NJ (US);

Inventors:

Brian E. Cathers, San Diego, CA (US);

Matthew Daniel Correa, San Diego, CA (US);

Joshua Hansen, La Jolla, CA (US);

Antonia Lopez-Girona, San Diego, CA (US);

Ehab M. Khalil, Yorktown, VA (US);

Kyle MacBeth, San Francisco, CA (US);

Hon-Wah Man, Princeton, NJ (US);

George W. Muller, Rancho Santa Fe, CA (US);

Michael Pourdehnad, San Francisco, CA (US);

Raj Raheja, Poway, CA (US);

Assignee:

Celgene Corporation, Summit, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); C07D 209/34 (2006.01); A61K 45/06 (2006.01); C07D 401/14 (2006.01); C07D 401/04 (2006.01); A61K 31/4545 (2006.01); A61K 31/5377 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/496 (2006.01);
U.S. Cl.
CPC ...
A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 209/34 (2013.01);
Abstract

Compounds of formula I for treating, preventing or managing cancer are disclosed. Also disclosed are methods of treating, preventing or managing cancer, such as leukemia, comprising administering the compounds. In certain embodiments, the method of treatment comprise administering a compound provided herein in combination with a second agent. Pharmaceutical compositions and single unit dosage forms comprising the compounds are also disclosed.


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