The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2018

Filed:

Jan. 15, 2015
Applicant:

Canon U.s. Life Sciences, Inc., Rockville, MD (US);

Inventor:

Bradley Scott Denney, Irvine, CA (US);

Assignee:

Canon U.S. Life Sciences, Inc., Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06T 7/143 (2017.01); G01N 35/08 (2006.01); G06T 7/13 (2017.01); G06T 7/12 (2017.01); G06T 7/194 (2017.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
G01N 35/08 (2013.01); G06T 7/12 (2017.01); G06T 7/13 (2017.01); G06T 7/143 (2017.01); B01L 3/502784 (2013.01); G06T 2207/10024 (2013.01); G06T 2207/30108 (2013.01);
Abstract

A system and a method for slug edge detection in a microchannel of a microfluidic device is provided. Specifically, the system comprises an image sensor in communication with the microchannel. The microchannel has at least two fluid slugs each of which has a marker of different color providing color gradient across the edge between the adjacent fluid slugs. An edge score function is generated for each channel segmentation dividing the microchannel into two segments at a specific location along the microchannel. The edge score function is proportional to a between class variance for intensity values associated with the two selected channel segments. The edge location is determined as the location along the channel defining one of the channel segmentations based at least in part on the edge score function.


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