The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 08, 2018
Filed:
Oct. 07, 2016
Applicant:
Autotelic Llc, City of Industry, CA (US);
Inventors:
Vuong Trieu, Agoura Hills, CA (US);
Chulho Park, San Diego, CA (US);
Assignee:
AUTOTELIC, LLC, City of Industry, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/94 (2006.01); C07K 16/44 (2006.01);
U.S. Cl.
CPC ...
G01N 33/94 (2013.01); C07K 16/44 (2013.01); C07K 2317/565 (2013.01);
Abstract
Optimized affinity reagent compositions for binding paclitaxel, such as antibodies, antibody fragments, and antibody derivatives, related methods of use, and related kits, are provided herein. Affinity reagents that comprise one or more complementary determining regions (CDRs) optimized from anti-paclitaxel antibodies antibody 8A10 and 3C6 are specifically provided. The disclosed affinity reagents are useful for binding and detecting paclitaxel in a sample, such as for determining or optimizing future doses of paclitaxel in a subject that was previously administered with paclitaxel.