The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2018

Filed:

Jun. 18, 2013
Applicant:

Glycan Biosciences Llc, Philadelphia, PA (US);

Inventors:

Deirdre Roma Coombe, Wembleys Down Western Australia, AU;

Barbara Mulloy, South Mimms, GB;

Assignee:

GLYCAN BIOSCIENCES LLC, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); A61K 31/715 (2006.01); A61K 31/726 (2006.01); A61K 31/727 (2006.01); C40B 30/02 (2006.01); G06F 19/16 (2011.01); G06F 19/00 (2018.01);
U.S. Cl.
CPC ...
G01N 33/68 (2013.01); A61K 31/715 (2013.01); A61K 31/726 (2013.01); A61K 31/727 (2013.01); C40B 30/02 (2013.01); G06F 19/16 (2013.01); G06F 19/706 (2013.01); Y02A 90/26 (2018.01);
Abstract

Medicaments in the form of therapeutic molecules including inflammatory modulators are designed and selected. A target site is on Interleukin 13 (IL-13) in which a glycosaminoglycan (GAG) molecule or polyanionic glycoconjugate or anionic polysaccharide modulates IL-13 activity or function. The target site can include amino acids located in the AB loops and/or helix D of human IL-13 or its homolog or derivative. The IL-13 target site is used to design a medicament for modulating physiological processes. Therapeutic and prophylactic compositions can include the designed medicaments.


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