The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2018

Filed:

Dec. 20, 2013
Applicant:

Commonwealth Scientific and Industrial Research Organisation, Campbell, AU;

Inventors:

Michael Wayne Graham, Jindalee, AU;

Robert Norman Rice, Sinnamon Park, AU;

Peter Michael Waterhouse, Paddington, AU;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61K 48/00 (2006.01); C12N 9/10 (2006.01); C12N 9/12 (2006.01); C12N 9/50 (2006.01); C12N 15/63 (2006.01); C12N 15/69 (2006.01); C12N 15/82 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 48/00 (2013.01); C12N 9/1051 (2013.01); C12N 9/127 (2013.01); C12N 9/503 (2013.01); C12N 15/111 (2013.01); C12N 15/1131 (2013.01); C12N 15/63 (2013.01); C12N 15/69 (2013.01); C12N 15/8216 (2013.01); C12N 15/8218 (2013.01); C12N 15/8283 (2013.01); C12N 15/85 (2013.01); A01K 2217/05 (2013.01); C12N 2310/111 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); C12N 2320/10 (2013.01); C12N 2320/30 (2013.01); C12N 2330/30 (2013.01); C12N 2330/50 (2013.01); C12N 2330/51 (2013.01); C12N 2800/108 (2013.01); C12N 2830/00 (2013.01); C12N 2830/002 (2013.01); C12N 2830/15 (2013.01); C12N 2830/38 (2013.01); C12N 2830/42 (2013.01); C12N 2830/55 (2013.01); C12N 2830/60 (2013.01); C12N 2840/20 (2013.01);
Abstract

The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention utilizes recombinant DNA technology to post-transcriptionally modify or modulate the expression of a target gene in a cell, tissue organ or whole organism, thereby producing novel phenotypes. Novel synthetic genes and genetic constructs which are capable of repressing delaying or otherwise reducing the expression of an endogenous gene or target gene in an organism when introduced thereto are also provided.


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