The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 08, 2018
Filed:
May. 16, 2016
Applicants:
Brian M. Seifried, Cambridge, MA (US);
Bradley D. Olsen, Arlington, MA (US);
Inventors:
Brian M. Seifried, Cambridge, MA (US);
Bradley D. Olsen, Arlington, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/47 (2006.01); C07K 1/107 (2006.01); C07K 1/113 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4727 (2013.01); C07K 1/107 (2013.01); C07K 1/113 (2013.01); C07K 14/47 (2013.01); A61K 38/00 (2013.01);
Abstract
Disclosed are protein brushes that mimic mucin in physical and functional characteristics. The protein brushes have a variable number of tandem repeats similar to natural mucin and are modified at a number of their tyrosine residues to introduce brush substituents that mimic the hydrogel nature of mucin.