The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2018

Filed:

Apr. 08, 2015
Applicant:

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

Ulrich Lücking, Berlin, DE;

Pierre Wasnaire, Düsseldorf, DE;

Arne Scholz, Berlin, DE;

Philip Lienau, Berlin, DE;

Gerhard Siemeister, Berlin, DE;

Christian Stegmann, Berlin, DE;

Ulf Bömer, Glienicke, DE;

Kunzeng Zheng, Shanghai, CN;

Ping Gao, Shanghai, CN;

Gang Chen, Shanghai, CN;

Jiajun Xi, Shanghai, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/14 (2006.01); C07D 498/04 (2006.01); C07C 53/18 (2006.01); A61K 31/4375 (2006.01); A61K 31/519 (2006.01);
U.S. Cl.
CPC ...
C07D 498/14 (2013.01); A61K 31/4375 (2013.01); A61K 31/519 (2013.01); C07C 53/18 (2013.01); C07D 498/04 (2013.01);
Abstract

The present invention relates to novel macrocyclic compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).


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