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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9962465 B1

PDFFull Text
Date of Patent:
May. 08, 2018

Filed:

Jul. 06, 2016

Amelogenin-chitosan hydrogel for dentin hypersensitivity

Applicant:

University of Southern California, Los Angeles, CA (US);

Inventors:

Janet Moradian-Oldak, Los Angeles, CA (US);

Qichao Ruan, Alhambra, CA (US);

Kaushik Mukherjee, Los Angeles, CA (US);

Assignee:

University of Southern California, Los Angeles, CA (US);

Attorney:

Brooks Kushman P.C.

Primary Examiner:

Kartheinz R Skowronek

Assistant Examiner:

Ronald T Niebauer

Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61L 27/22 (2006.01); A61L 27/44 (2006.01); A61L 27/46 (2006.01); A61L 27/52 (2006.01);
U.S. Cl.
CPC ...
A61L 27/227 (2013.01); A61L 27/446 (2013.01); A61L 27/46 (2013.01); A61L 27/52 (2013.01); C07K 14/47 (2013.01); A61L 2430/12 (2013.01);
Abstract

A method to regrow a protective layer over exposed/demineralized dentin that includes a step of identifying a subject having exposed/demineralized dentin. The demineralized dentin is contacted with a remineralization composition that includes an amelogenin and derived peptides, a chitosan, water, and a sufficient amount of a pH adjusting component such that the composition has a pH greater than about 6.0 such that dentinal tubules are occluded with apatite crystals and enamel is regrown on the dentinal tubules.

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Moradian-Oldak, Janet. (2018). Amelogenin-chitosan hydrogel for dentin hypersensitivity (U.S. Patent No. 9962465). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9962465

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