The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2018

Filed:

Apr. 03, 2014
Applicant:

Ufpeptides S.r.l., Bologna, IT;

Inventors:

Remo Guerrini, Ferrara, IT;

Severo Salvadori, Ferrara, IT;

Girolamo Calo′, Ferrara, IT;

Assignee:

UFPEPTIDES S.R.L., Ferrara, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); A61K 47/48 (2006.01); A61K 38/17 (2006.01); A61K 47/54 (2017.01); A61K 47/55 (2017.01);
U.S. Cl.
CPC ...
A61K 47/48061 (2013.01); A61K 38/1787 (2013.01); A61K 47/543 (2017.08); A61K 47/545 (2017.08); A61K 47/55 (2017.08); C07D 403/14 (2013.01);
Abstract

The invention relates to a supramolecular aggregate of formula (VI) wherein A is an active substance, and X, X, Xand X, independently to each other, are a moiety of Formula (I) containing a maleimido functionalization and at least one among X, X, Xand Xis present in Formula (VI). In a preferred embodiment the maleimido-functionalized core is PWT2. The supra-molecular aggregate can be used in the field of drugs, vaccines, as ligands for GPCR, i.e. agonists as well as antagonist, as antibiotics and as diagnostics eventually in complex with radionuclides.


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