The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2018

Filed:

Jul. 11, 2016
Applicant:

Ottawa Hospital Research Institute, Ottawa, CA;

Inventors:

Colin Suen, Ottawa, CA;

Lynn Megeney, Ottawa, CA;

Duncan J. Stewart, Ottawa, CA;

Mohammad Abdul-Ghani, Ottawa, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 9/04 (2006.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); C07K 14/52 (2006.01); C07K 14/54 (2006.01);
U.S. Cl.
CPC ...
A61K 38/19 (2013.01); A61K 38/20 (2013.01); A61K 38/204 (2013.01); C07K 14/52 (2013.01); C07K 14/54 (2013.01); C07K 14/5412 (2013.01);
Abstract

A method is disclosed for inducing right ventricular (RV) adaptive remodeling in a patient suffering from pulmonary hypertension (PH) due to pressure overload comprising administering a therapeutically effective amount of a carditrophin-1 polypeptide, recombinant protein or a polynucleotide encoding CT-1 polypeptide or full-length protein.


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