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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9962389 B1

PDFFull Text
Date of Patent:
May. 08, 2018

Filed:

Apr. 14, 2017

4-aryl-n-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group

Applicant:

Bayer Intellectual Property Gmbh, Monheim, DE;

Inventors:

Ulrich Lücking, Berlin, DE;

Rolf Bohlmann, Berlin, DE;

Arne Scholz, Berlin, DE;

Gerhard Siemeister, Berlin, DE;

Mark Jean Gnoth, Mettmann, DE;

Ulf Bömer, Glienicke, DE;

Dirk Kosemund, Berlin, DE;

Philip Lienau, Berlin, DE;

Gerd Rühter, Hamburg, DE;

Carsten Schultz-Fademrecht, Dortmund, DE;

Assignee:

Bayer Intellectual Property GmbH, Monheim, DE;

Attorney:

Morrison & Foerster LLP

Primary Examiner:

Venkataraman Balasubramanian

Int. Cl.
CPC ...
C07D 251/44 (2006.01); C07D 251/42 (2006.01); C07D 251/22 (2006.01); C07D 251/16 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07C 381/10 (2006.01); A61K 31/53 (2006.01); A61P 35/00 (2006.01); C07D 405/04 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/53 (2013.01); C07B 59/002 (2013.01); C07C 381/10 (2013.01); C07D 251/16 (2013.01); C07D 251/22 (2013.01); C07D 251/42 (2013.01); C07D 251/44 (2013.01); C07D 401/12 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07B 2200/05 (2013.01);
Abstract

The present invention relates to 4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group of general formula (I) or (Ia) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I) or (Ia).

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