The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 01, 2018

Filed:

Mar. 03, 2009
Applicants:

E. J. Delikatny, Havertown, PA (US);

Anatoliy V. Popov, Philadelphia, PA (US);

Gang Zheng, Toronto, CA;

Theresa Mawn, Bronx, NY (US);

Inventors:

E. J. Delikatny, Havertown, PA (US);

Anatoliy V. Popov, Philadelphia, PA (US);

Gang Zheng, Toronto, CA;

Theresa Mawn, Bronx, NY (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 8/00 (2006.01); A61B 10/00 (2006.01); C12Q 1/61 (2006.01); A61K 49/00 (2006.01); G01N 33/50 (2006.01); G01N 33/542 (2006.01); G01N 33/574 (2006.01); A61K 41/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/61 (2013.01); A61K 49/0036 (2013.01); G01N 33/5011 (2013.01); G01N 33/542 (2013.01); G01N 33/57484 (2013.01); A61K 41/0071 (2013.01); A61K 49/0017 (2013.01); A61K 49/0032 (2013.01);
Abstract

The present invention is directed to a phospholipid-based NIR molecular beacon, having a phospholipid moiety; with an NIR fluorophore moiety covalently linked to a phospholipid glycerol backbone and a quencher moiety covalently linked to the phospholipid glycerol backbone. Additionally, provided herein is methods of analyzing a sample for the presence of a phospholipase and methods of identifying the activity of a phospholipase in vivo utilizing phospholipid-based NIR molecular beacon.


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