The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2018
Filed:
Nov. 09, 2015
Applicants:
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Ludwig Institute for Cancer Research Ltd., New York, NY (US);
Inventors:
Dinah Sah, Hopkinton, MA (US);
Pamela Tan, Kulmbach, DE;
Webster Cavenee, La Jolla, CA (US);
Frank Furnari, La Jolla, CA (US);
Maria del Mar Inda Perez, La Jolla, CA (US);
Rudy Bonavia, La Jolla, CA (US);
Assignees:
ALNYLAM PHARMACEUTICALS, INC., Cambridge, MA (US);
LUDWIG INSTITUTE FOR CANCER RESEARCH LTD., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); A61K 31/713 (2013.01); C12N 15/1136 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3515 (2013.01); C12N 2320/30 (2013.01); C12N 2320/31 (2013.01);
Abstract
The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a mutant Epidermal Growth Factor Receptor (EGFR), and methods of using the dsRNA to inhibit expression of mutant EGFR.