The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2018
Filed:
Apr. 09, 2015
Applicant:
Universitatsklinikum Hamburg-eppendorf, Hamburg, DE;
Inventors:
Wolfram-Hubertus Zimmermann, Hamburg, DE;
Thomas Eschenhagen, Hamburg, DE;
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); C12M 3/00 (2006.01); C12M 1/42 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); C12M 21/08 (2013.01); C12M 35/04 (2013.01); C12N 2506/02 (2013.01);
Abstract
The invention is directed to a method for the preparation of a multiring engineered heart tissue construct suitable for use in cardiac tissue augmentation and/or replacement therapy. The invention further refers to multiring EHT constructs which comprise at least two force-generating engineered heart tissue rings fused with each other and a device for preparing the same. Finally, the invention relates to force-generating engineered heart tissue rings derived from human cells and their use in drug screening and target validation assays.