The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2018
Filed:
Mar. 30, 2015
Applicant:
Alderbio Holdings Llc, Las Vegas, NV (US);
Inventors:
Jeffrey T. L. Smith, Bellevue, WA (US);
Leon F. Garcia-Martinez, Woodinville, WA (US);
Andrew L. Feldhaus, Lynnwood, WA (US);
Assignee:
ALDERBIO HOLDINGS LLC, Las Vegas, NV (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); A61K 39/395 (2006.01); A61K 31/454 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01); A61K 38/20 (2006.01); G01N 33/574 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/248 (2013.01); A61K 31/454 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 38/204 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); G01N 33/57407 (2013.01); G01N 33/57484 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); G01N 2800/52 (2013.01);
Abstract
The present invention is directed to therapeutic methods using IL-6 antagonists such as anti-IL-6 antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat mucositis (e.g., oral mucositis) including persons on a treatment regimen with a drug or chemotherapy and/or radiation for cancer (e.g., head and neck cancer) that is associated with increased risk of mucositis, including oral mucositis.