The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 01, 2018

Filed:

Feb. 28, 2014
Applicant:

Riken, Wako-shi, Saitama, JP;

Inventors:

Atsushi Miyawaki, Wako, JP;

Akiko Kumagai, Wako, JP;

Assignee:

RIKEN, Wako-Shi, Saitama, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 33/52 (2006.01); C07K 14/46 (2006.01); G01N 33/72 (2006.01); C07K 14/00 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C07K 14/461 (2013.01); C07K 14/00 (2013.01); C12Q 1/6816 (2013.01); G01N 33/72 (2013.01); C07K 2319/60 (2013.01); G01N 2800/085 (2013.01); G01N 2800/22 (2013.01);
Abstract

In order to provide a novel fluorescent protein and use thereof, the polypeptide according to the present invention has fluorescent properties in the presence of bilirubin and includes (1) the amino acid sequence of SEQ ID NO: 1, (2) an amino acid sequence having, for example, substitution of 1 to 21 amine acids in the amino acid sequence of SEQ ID NO: 1, (3) an amino acid sequence having 85% or more sequence identity to the amino acid sequence of SEQ ID NO: 1, or (4) the amino acid sequence encoded by a polynucleotide that hybridizes with a polynucleotide consisting of a sequence complementary to the polynucleotide encoding the polypeptide according to the amino acid sequence in (1) under a stringent condition.


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