The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2018
Filed:
Sep. 12, 2014
Salk Institute for Biological Studies, La Jolla, CA (US);
Sanofi, Paris, FR;
Magda Stankova, Tucson, AZ (US);
Fahad Al-Obeidi, Tucson, AZ (US);
Jacques Mauger, Oro Valley, AZ (US);
Robert A. Binnie, Tucson, AZ (US);
Tony Hunter, Del Mar, CA (US);
Jill Meisenhelder, Vista, CA (US);
Stephen Rush Fuhs, San Diego, CA (US);
Salk Institute for Biological Studies, La Jolla, CA (US);
Sanofi, Paris, FR;
Abstract
A peptide is disclosed of the general structure: Z—W—Y, wherein Z and Y are independently a one to eight amino acid sequence wherein the amino acids are selected from glycine and alanine and W is a non-hydrolyzable pHis analogue. Such peptides can be used to produce sequence-independent anti-phosphohistidine antibodies. Also provided are antibodies that specifically bind to a peptide comprising a phosphohistidine (or a non-hydrolyzable pHis analogue) but fail to specifically bind to an identical peptide containing histidine instead of phosphohistidine.