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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9957275 B1

PDFFull Text
Date of Patent:
May. 01, 2018

Filed:

Jun. 30, 2017

Pyrazolo[1,5-a]pyrimidines for antiviral treatment

Applicant:

Gilead Sciences, Inc., Foster City, CA (US);

Inventors:

Kerim Babaoglu, Lansdale, PA (US);

Constantine G. Boojamra, San Francisco, CA (US);

Eugene J. Eisenberg, San Carlos, CA (US);

Hon Chung Hui, San Mateo, CA (US);

Richard L. Mackman, Millbrae, CA (US);

Jay P. Parrish, El Dorado Hills, CA (US);

Michael Sangi, San Mateo, CA (US);

Oliver L. Saunders, Clovis, CA (US);

Dustin Siegel, Half Moon Bay, CA (US);

David Sperandio, Palo Alto, CA (US);

Hai Yang, San Mateo, CA (US);

Assignee:

Gilead Sciences, Inc., Foster City, CA (US);

Attorney:
Primary Examiner:

Bruck Kifle

Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 487/08 (2006.01); C07D 495/04 (2006.01); C07D 513/04 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61K 31/551 (2006.01); A61K 31/675 (2006.01); C07F 9/6561 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 31/55 (2013.01); A61K 31/551 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); C07D 495/04 (2013.01); C07D 513/04 (2013.01); C07D 519/00 (2013.01); C07F 9/65616 (2013.01);
Abstract

The invention provides compounds of Formula I or Formula II: or a pharmaceutically acceptable salt or ester, thereof, as described herein. The compounds and compositions thereof are useful for treating Pneumovirinae virus infections. The compounds, compositions, and methods provided are particularly useful for the treatment of Human respiratory syncytial virus infections.

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