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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9957274 B1

PDFFull Text
Date of Patent:
May. 01, 2018

Filed:

May. 05, 2017

Indane inhibitors of eed and methods of their use

Applicant:

Abbvie Inc., North Chicago, IL (US);

Inventors:

Michael R. Michaelides, Libertyville, IL (US);

Michael L. Curtin, Pleasant Prairie, WI (US);

Huan-Qiu Li, Wilmette, IL (US);

Marina A Pliushchev, Vernon Hills, IL (US);

Ying Wang, Libertyville, IL (US);

Hongyu H. Zhao, Libertyville, IL (US);

Richard F. Clark, Gurnee, IL (US);

Alan S. Florjancic, Kenosha, WI (US);

Zhiqin Ji, Libertyville, IL (US);

Mariazel Torrent, Lake Bluff, IL (US);

Ramzi F. Sweis, Lake Bluff, IL (US);

Anil Vasudevan, Union Grove, WI (US);

Justin D. Dietrich, Lidenhurst, IL (US);

Assignee:

AbbVie Inc., North Chicago, IL (US);

Attorney:

Changxia Sun

Primary Examiner:

Rebecca L Anderson

Assistant Examiner:

Karen Cheng

Int. Cl.
CPC ...
C07D 207/14 (2006.01); A61K 31/40 (2006.01); C07D 487/04 (2006.01); C07D 403/10 (2006.01); C07D 405/04 (2006.01); C07D 413/10 (2006.01); C07D 403/12 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/40 (2013.01); C07D 207/14 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/10 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/04 (2013.01); C07D 413/10 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01);
Abstract

Compounds having a structure of Formula (I): or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein A, A, A, A, A, n, and m are as defined herein and are provided. Pharmaceutical compositions comprising such compounds and methods for treating various EED-related conditions or diseases, including cancer, by administration of such compounds are also provided.

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