The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 01, 2018

Filed:

Dec. 22, 2015
Applicant:

Shenzhen Neptunus Pharmaceutical Research Institute Co., Ltd., Shenzhen, CN;

Inventors:

Tian Tang, Shenzhen, CN;

Feng Jin, Shenzhen, CN;

Yanqing Wang, Shenzhen, CN;

Jing Wu, Shenzhen, CN;

Xiarou Liu, Shenzhen, CN;

Jing'an Yang, Shenzhen, CN;

Hanlin Feng, Shenzhen, CN;

Lin Yu, Shenzhen, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 239/94 (2006.01); C07C 309/30 (2006.01);
U.S. Cl.
CPC ...
C07D 239/94 (2013.01); C07C 309/30 (2013.01); C07B 2200/13 (2013.01);
Abstract

Provided is a composition of N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(ethoxy)-6-quinazolinyl]-4-(dimethylamino)-2-butenamide p-toluene sulfonate 1.5 hydrate α-polymorph. The α-polymorph has a stable form, a defined melting point, a good chemical stability, and a good endurance to high temperature and light irradiation, and is suitable for pharmaceutical use.


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