The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2018
Filed:
May. 06, 2016
Applicant:
Incanthera Ltd, Manchester, GB;
Inventors:
Jason Gill, Leeds, GB;
Paul Loadman, Bradford, GB;
Rob Falconer, Bradford, GB;
Laurence Patterson, West Yorkshire, GB;
Jennifer Xavier, Needingworth, GB;
Michael Bibby, Bingley, GB;
Assignee:
INCANTHERA LTD, Manchester, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/06 (2006.01); A61K 47/48 (2006.01); A61K 31/165 (2006.01); A61K 31/704 (2006.01); A61K 47/65 (2017.01); A61K 47/60 (2017.01); A61K 47/55 (2017.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); A61K 31/165 (2013.01); A61K 31/704 (2013.01); A61K 47/55 (2017.08); A61K 47/60 (2017.08); A61K 47/65 (2017.08); C07K 7/06 (2013.01);
Abstract
The present invention relates to compounds, and pharmaceutically acceptable salts thereof, comprising a vascular disrupting agent (VDA) associated and a MMP proteolytic cleavage site. The compounds are useful in the treatment of cancer.