The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2018
Filed:
Jan. 23, 2017
Applicants:
Children's Hospital Los Angeles, Los Angeles, CA (US);
Nanovalent Pharmaceuticals, Inc., Bozeman, MT (US);
Inventors:
Jon O. Nagy, Bozeman, MT (US);
Timothy Triche, Los Angeles, CA (US);
Hyung-Gyoo Kang, Buena Park, CA (US);
Sheetal Mitra, Los Angeles, CA (US);
Assignees:
Children's Hospital Los Angeles, Los Angeles, CA (US);
Nanovalent Pharmaceuticals, Inc., Bozeman, MT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); C12N 15/113 (2010.01); C07K 16/30 (2006.01); A61K 31/704 (2006.01); A61K 31/4745 (2006.01); A61K 33/24 (2006.01); A61K 31/573 (2006.01); A61K 31/7068 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1271 (2013.01); A61K 31/4745 (2013.01); A61K 31/573 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 33/24 (2013.01); A61K 48/0058 (2013.01); A61K 48/0066 (2013.01); C07K 16/3061 (2013.01); C12N 15/113 (2013.01); C12N 15/1135 (2013.01); C07K 2317/55 (2013.01); C07K 2317/626 (2013.01); C12N 2310/11 (2013.01); C12N 2320/32 (2013.01);
Abstract
Provided herein are compositions and methods for treating cancer in a subject in need thereof. The methods include using hybrid polymerized liposomal nanoparticles comprising, both polymerizable lipids and non-polymerizable lipids. The nanoparticles further comprise targeting agents and therapeutic agents.