The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2018
Filed:
Apr. 21, 2011
Marco Gil, Odivelas, PT;
Constanca Cacela, Rio Maior, PT;
Ricardo Mendonca, Feijo, PT;
Filipe Gaspar, Oeiras, PT;
Marco Gil, Odivelas, PT;
Constanca Cacela, Rio Maior, PT;
Ricardo Mendonca, Feijo, PT;
Filipe Gaspar, Oeiras, PT;
HOVIONE INTER LIMITED, Lucerne, CH;
Abstract
A process for reducing the particle size of an active pharmaceutical ingredient (API) while maintaining its polymorphic form, comprises the step of processing the active pharmaceutical ingredient by cavitation at elevated pressure. The process preferably comprises the step of isolating the processed active ingredient in the form of powder, wherein the isolation step comprises filtration or spray drying. Particles produced by the process of the invention typically have a span value of less than 2.5.