The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
Sep. 22, 2016
Applicant:
City of Hope, Duarte, CA (US);
Inventors:
John J. Rossi, Azusa, CA (US);
Ola Snove, Oslo, NO;
Ali Ehsani, West Covina, CA (US);
Pal Saetrom, Trondheim, NO;
Britta Vallazza, Hagen, DE;
Jane Zhang, South El Monte, CA (US);
Lars Aagaard, Ry, DK;
Assignee:
City of Hope, Duarte, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G06F 19/18 (2011.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C40B 30/02 (2006.01); G06F 19/22 (2011.01);
U.S. Cl.
CPC ...
G06F 19/18 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/1132 (2013.01); C12N 15/1135 (2013.01); C12N 15/1138 (2013.01); C40B 30/02 (2013.01); G06F 19/22 (2013.01); C12N 2310/14 (2013.01); C12N 2310/51 (2013.01); C12N 2310/53 (2013.01); C12N 2320/30 (2013.01);
Abstract
The present invention relates to novel short interfering RNA (siRNA) molecules that are multi-targeted. More specifically, the present invention relates to siRNA molecules that target two or more sequences. In one embodiment, multi-targeting siRNA molecules are designed to incorporate features of siRNA molecules and features of micro-RNA (miRNA) molecules. In another embodiment, multi-targeting siRNA molecules are designed so that each strand is directed to separate targets.