The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 24, 2018

Filed:

May. 23, 2012
Applicants:

Takuji Matsumoto, Ibaraki-ken, JP;

Mitsuaki Yamamoto, Chiba-ken, JP;

Inventors:

Takuji Matsumoto, Ibaraki-ken, JP;

Mitsuaki Yamamoto, Chiba-ken, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/86 (2006.01); G01N 33/541 (2006.01); G01N 33/542 (2006.01); G01N 33/82 (2006.01);
U.S. Cl.
CPC ...
G01N 33/86 (2013.01); G01N 33/541 (2013.01); G01N 33/542 (2013.01); G01N 33/82 (2013.01);
Abstract

A problem to be solved by the present invention is to inhibit a nonspecific agglutination reaction in an agglutination test using a monoclonal antibody having a property of specifically biding to PIVKA-II and a monoclonal antibody having a property of specifically biding to prothrombin as well as two types of carrier particles carrying these monoclonal antibodies. The nonspecific agglutination reaction can be inhibited by adding certain divalent metal ions to a reaction solution containing the monoclonal antibody having a property of specifically biding to PIVKA-II and the monoclonal antibody having a property of specifically biding to prothrombin as well as the two types of carrier particles carrying these monoclonal antibodies.


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