The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
Mar. 21, 2012
Penelope Kay-fedorov, Hannover, DE;
Martin Messerle, Hannover, DE;
Thomas F. Schulz, Hannover, DE;
Lars Steinbrück, Hannover, DE;
Ildar Gabaev, Hannover, DE;
Penelope Kay-Fedorov, Hannover, DE;
Martin Messerle, Hannover, DE;
Thomas F. Schulz, Hannover, DE;
Lars Steinbrück, Hannover, DE;
Ildar Gabaev, Hannover, DE;
Medizinische Hochschule Hannover, Hannover, DE;
Abstract
The present invention relates to a new binder molecule useful e.g. as an immune suppressor. In particular, it has been recognized that the UL11 protein of human the cytomegalovirus, binds to the CD45 molecule, potentially altering the immune system of an individual. In addition, the present invention relates to binder molecules, in particular, fusion molecules containing the CD45 binding domain of the UL11 protein in combination with a second molecule of interest for delivery of said molecule to cells expressing the CD45 molecule. Moreover, the present invention relates to pharmaceutical compositions comprising the UL11 protein of human cytomegalovirus, or derivatives or homologs thereof, or a nucleic acid sequence encoding the same.