The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
May. 07, 2012
Francesca Demichelis, New York, NY (US);
Karl Garsha, Sahuarita, AZ (US);
Phillip C. Miller, Tucson, AZ (US);
Ray B. Nagle, Tucson, AZ (US);
Michael Otter, Tucson, AZ (US);
Gary Anthony Pestano, Lafayette, CO (US);
Mark Rubin, New York, NY (US);
Francesca Demichelis, New York, NY (US);
Karl Garsha, Sahuarita, AZ (US);
Phillip C. Miller, Tucson, AZ (US);
Ray B. Nagle, Tucson, AZ (US);
Michael Otter, Tucson, AZ (US);
Gary Anthony Pestano, Lafayette, CO (US);
Mark Rubin, New York, NY (US);
Ventana Medical Systems, Inc., Tucson, AZ (US);
Cornell University, Ithaca, NY (US);
Abstract
In general, the presently disclosed technology relates to identification of cancer subtypes. More specifically, the technology relates to methods for determining molecular drivers of cancer and/or progression using a multivariate image data and statistical analysis of in-situ molecular markers and morphological characteristics in the same cells of a biological sample suspected of b cancer. This analysis takes place after a single acquisition that obtains the molecular and anatomic morphology data in parallel. The analysis compares specific morphological and molecular markers to known samples exhibiting particular genetic drivers of the cancer. This method provides statistical information that allows for an increased confidence in the identification of specific molecular drivers of the cancer.