The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 24, 2018

Filed:

Dec. 18, 2015
Applicant:

R.p. Scherer Technologies, Llc, Carson City, NV (US);

Inventors:

David Rabuka, Kensington, CA (US);

Gregory W. deHart, El Cerrito, CA (US);

Patrick Holder, Oakland, CA (US);

Jeanne Baker, Redwood City, CA (US);

Assignee:

R.P. Scherer Technologies, LLC, Carson City, NV (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 19/00 (2006.01); C07K 16/00 (2006.01); A61K 38/00 (2006.01); C12N 9/02 (2006.01); C12P 21/00 (2006.01); C07K 16/32 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
C12P 21/005 (2013.01); A61K 47/68 (2017.08); C07K 16/00 (2013.01); C07K 16/32 (2013.01); C12N 9/0051 (2013.01); C07K 2317/14 (2013.01); C07K 2317/40 (2013.01); C12Y 108/99 (2013.01);
Abstract

The present disclosure provides activated formylglycine-generating enzymes (FGE), methods of producing activated FGE, and their use in methods of producing a protein comprising a formylglycine (FGly) residue. The methods of producing activated FGE, as well as methods of use of activated FGE in producing FGly-containing proteins, include both cell-based and cell-free methods. Compositions and kits that find use, e.g., in practicing the methods of the present disclosure are also provided.


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