The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
Oct. 09, 2015
Applicant:
Genvec, Inc., Gaithersburg, MD (US);
Inventors:
Douglas E. Brough, Gaithersburg, MD (US);
Damodar R. Ettyreddy, Clarksburg, MD (US);
Assignee:
GenVec, Inc., Gaithersburg, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/861 (2006.01); C12N 15/86 (2006.01); A61K 38/16 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 38/16 (2013.01); A61K 48/0058 (2013.01); A61K 48/0075 (2013.01); A61K 48/00 (2013.01); C12N 2710/10043 (2013.01); C12N 2710/10343 (2013.01); C12N 2830/008 (2013.01);
Abstract
The invention is directed to a replication-deficient adenoviral vector comprising a nucleic acid sequence encoding a human atonal homolog-1 (Hath1) protein operably linked to a human glial fibrillary acidic protein (GFAP) promoter. The invention also is directed to a composition and method utilizing the adenoviral vector to generate sensory cells in the inner ear of a human.