The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
May. 31, 2012
Donald E. Ingber, Boston, MA (US);
Yusuke Torisawa, Kyoto, JP;
Geraldine Hamilton, Cambridge, MA (US);
Akiko Mammoto, Brookline, MA (US);
Tadanori Mammoto, Brookline, MA (US);
Catherine Spina, Boston, MA (US);
Donald E. Ingber, Boston, MA (US);
Yusuke Torisawa, Kyoto, JP;
Geraldine Hamilton, Cambridge, MA (US);
Akiko Mammoto, Brookline, MA (US);
Tadanori Mammoto, Brookline, MA (US);
Catherine Spina, Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Children's Medical Center Corporation, Boston, MA (US);
Abstract
The technology described herein is directed to methods and devices that can be used to induce functional organ structures to form within an implantation device by implanting it in vivo within the body of a living animal, and allowing cells and tissues to impregnate the implantation device and establish normal microenvironmental architecture and tissue-tissue interfaces. Then the contained cells and tissues can be surgically removed intact and either transplanted into another animal or maintained ex vivo by perfusing it through one or more of the fluid channels with medium and/or gases necessary for cell survival.