The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
Jun. 01, 2015
Applicant:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Inventors:
Thomas Nittoli, Pearl River, NY (US);
Arthur Kunz, New City, NY (US);
Assignee:
REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); A61K 47/48384 (2013.01); A61K 47/48438 (2013.01); A61K 47/48561 (2013.01); A61K 47/48569 (2013.01); A61K 47/48715 (2013.01); C07K 16/30 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present disclosure relates to conjugates comprising biologically active molecules linked to a multimeric antigen-binding compound or a multimeric immunoglobulin via a linker. The disclosure further provides reagents and methods of manufacturing the conjugates and the linkers. The disclosure also provides compositions comprising the conjugates, methods of modifying abnormal cell growth and methods of treatment using the conjugates or the compositions.