The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
Sep. 24, 2015
Applicants:
The Regents of the University of California, Oakland, CA (US);
The Scripps Research Institute, La Jolla, CA (US);
Inventors:
Leonard H. Rome, Los Angeles, CA (US);
Valerie A. Kickhoefer, Sherman Oaks, CA (US);
Glen Nemerow, La Jolla, CA (US);
Cheng-Yu Lai, La Jolla, CA (US);
Christopher Wiethoff, Downers Grove, IL (US);
Mu Han, Los Angeles, CA (US);
Assignees:
The Regets of the University of California, Oakland, CA (US);
The Scripps Research Institute, La Jolla, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); C12N 15/87 (2006.01); C12N 15/88 (2006.01); C07K 14/435 (2006.01); C12N 9/10 (2006.01); C07K 14/485 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); C07K 14/435 (2013.01); C07K 14/485 (2013.01); C12N 9/1077 (2013.01); C12N 15/87 (2013.01); C12N 15/88 (2013.01); C07K 2319/00 (2013.01); C07K 2319/70 (2013.01); C07K 2319/75 (2013.01); C12N 2710/10322 (2013.01); C12Y 204/0203 (2013.01);
Abstract
The invention relates to compositions of vault complexes containing recombinant membrane lytic proteins, such as an adenovirus protein VI lytic domain, and methods of using the vault complexes to facilitate delivery and entry of a biomolecule into a cell or subject.