The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
Jun. 18, 2014
Applicant:
4sc Discovery Gmbh, Planegg-Martinsried, DE;
Inventors:
Fritz Aberger, Salzburg, AT;
Wolfgang Gruber, Salzburg, AT;
Johann Leban, Vienna, AT;
Hella Kohlhof, Munich, DE;
Daniel Vitt, Germering, DE;
Roland Baumgartner, Planegg-Martinsried, DE;
Assignee:
4 SC AG, Planegg-Martinsried, DE;
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); A61K 31/00 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/00 (2013.01); A61K 31/506 (2013.01);
Abstract
The present invention relates to a DYRK1B inhibitor for use in the treatment of cancer, wherein in said cancer and/or in cells of said cancer the hedgehog signaling pathway is activated, and in particular the activation of the hedgehog signaling pathway is independent of signaling by the G protein-coupled receptor Smoothened.