The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 24, 2018

Filed:

Feb. 19, 2016
Applicants:

D. Tyler Mcquade, Tallahassee, FL (US);

Frank B. Gupton, Tallahassee, FL (US);

Ashley R. Longstreet, Tallahassee, FL (US);

Suzanne M. Opalka, Tallahassee, FL (US);

Inventors:

D. Tyler McQuade, Tallahassee, FL (US);

Frank B. Gupton, Tallahassee, FL (US);

Ashley R. Longstreet, Tallahassee, FL (US);

Suzanne M. Opalka, Tallahassee, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 213/85 (2006.01); C07D 217/26 (2006.01); C07D 221/10 (2006.01); C07D 221/16 (2006.01); C07D 409/04 (2006.01);
U.S. Cl.
CPC ...
C07D 213/85 (2013.01); C07D 217/26 (2013.01); C07D 221/10 (2013.01); C07D 221/16 (2013.01); C07D 409/04 (2013.01);
Abstract

A method of making a 2-halonicotinonitrile comprises reacting an alkylidene nitrile with a C1-compound in an organic solvent and a dehydrating agent. The dehydrating agent substantially retards dimerization of the alkylidene nitrile during the reaction. The enamine intermediate that forms from the reaction is cyclized using a halide donor to make the 2-halonicotinonitrile.


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